ARC (C-Term) Peptide
Reactivity: Human
Host: Synthetic
BP, WB
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- Target
- ARC
- Protein Region
- C-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- RHPLPKTLEQ LIQRGMEVQD DLEQAAEPAG PHLPVEDEAE TLTPAPNSES
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ARC Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- ARC
- Synonyms
- activity regulated cytoskeleton associated protein Peptide, Arc Peptide
- Background
-
ARC is required for consolidation of synaptic plasticity as well as formation of long-term memory. It regulates endocytosis of AMPA receptors in response to synaptic activity. It is required for homeostatic synaptic scaling of AMPA receptors. ARC plays a role in the regulation of cell morphology and cytoskeletal organization and is required in the stress fiber dynamics and cell migration.
Alias Symbols: Arg3.1
Protein Size: 396 - Molecular Weight
- 43 kDa
- Gene ID
- 23237
- NCBI Accession
- NM_015193, NP_056008
- UniProt
- Q7LC44
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