Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1) (N-Term) Peptide
MAPKSP1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MAPKSP1 products
- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LPSVEGLHAI VVSDRDGVPV IKVANDNAPE HALRPGFLST FALATDQGSK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-LAMTOR3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MAPKSP1 (Mitogen-Activated Protein Kinase Kinase 1 Interacting Protein 1 (MAPKSP1))
- Synonyms
- MAPKSP1 Peptide, MAP2K1IP1 Peptide, MAPBP Peptide, MP1 Peptide, PRO0633 Peptide, Ragulator3 Peptide, AW556229 Peptide, Map2k1ip1 Peptide, Mapbp Peptide, Mapksp1 Peptide, Mp1 Peptide, mapksp1 Peptide, zgc:110207 Peptide, late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 Peptide, LAMTOR3 Peptide, Lamtor3 Peptide, lamtor3 Peptide
- Background
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This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13.
Alias Symbols: MAP2K1IP1, MAPBP, MAPKSP1, MP1, PRO0633, Ragulator3
Protein Size: 124 - Molecular Weight
- 13 kDa
- Gene ID
- 8649
- NCBI Accession
- NM_021970, NP_068805
- UniProt
- Q9UHA4
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