Thioredoxin Interacting Protein (TXNIP) (N-Term) Peptide
TXNIP
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN2183818
$160.46
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 11 to 17 Business Days
Quick Overview for Thioredoxin Interacting Protein (TXNIP) (N-Term) Peptide (ABIN2183818)
Target
TXNIP
(Thioredoxin Interacting Protein (TXNIP))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
-
-
Protein Region
- N-Term
-
Sequence
- QTSEYLRYED TLLLEDQPTG ENEMVIMRPG NKYEYKFGFE LPQGPLGTSF
-
Characteristics
- This is a synthetic peptide designed for use in combination with anti-TXNIP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
Purification
- Purified
-
-
-
-
Application Notes
- Optimal working dilution should be determined by the investigator.
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
Concentration
- 1 mg/mL
-
Buffer
- Final peptide concentration is 1 mg/mL in PBS.
-
Handling Advice
- Avoid repeat freeze-thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
Background
-
TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
Protein Size: 391 -
Molecular Weight
- 43 kDa
-
Gene ID
- 10628
-
NCBI Accession
- XP_003960219
-
UniProt
- Q9H3M7
Target
-
You are here:
