Thioredoxin Interacting Protein (TXNIP) Peptide
TXNIP
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN937587
$398.38
Plus shipping costs $50.00
100 μg
Shipping to:
United States
Delivery in 16 to 22 Business Days
Quick Overview for Thioredoxin Interacting Protein (TXNIP) Peptide (ABIN937587)
Target
TXNIP
(Thioredoxin Interacting Protein (TXNIP))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
-
-
Peptide Type
- Synthetic
-
Sequence
- DTPEAPPCYM DVIPEDHRLE SPTTPLLDDM DGSQDSPIFM YAPEFKFMPP
-
Characteristics
-
A synthetic peptide for use as a blocking control in assays to test for specificity of TXNIP antibody,
Alternative Names: TXNIP control peptide, TXNIP antibody Blocking Peptide, Anti-TXNIP Blocking Peptide, Thioredoxin Interacting Protein Blocking Peptide, EST01027 Blocking Peptide, HHCPA78 Blocking Peptide, THIF Blocking Peptide, VDUP1 Blocking Peptide
-
-
-
-
Application Notes
- Optimal conditions should be determined by the investigator
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
-
Buffer
- PBS
-
Handling Advice
- Avoid repeated freeze/thaw cycles.
-
Storage
- -20 °C
-
Storage Comment
- Store at -20 °C long term.
-
-
- TXNIP (Thioredoxin Interacting Protein (TXNIP))
-
Background
- TXNIP may act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. It interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. It functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. It is required for the maturation of natural killer cells.
-
Molecular Weight
- 44 kDa
Target
-
You are here:
