Platelet-Derived Growth Factor C (PDGFC) (N-Term) Peptide
PDGFC
Reactivity: Human, Mouse
Host: Synthetic
BP, WB
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- Target See all PDGFC products
- PDGFC (Platelet-Derived Growth Factor C (PDGFC))
- Protein Region
- N-Term
- Origin
- Human, Mouse
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MLLLGLLLLT SALAGQRTGT RAESNLSSKL QLSSDKEQNG VQDPRHERVV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-Pdgfc Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeat freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PDGFC (Platelet-Derived Growth Factor C (PDGFC))
- Synonyms
- SCDGF Peptide, FALLOTEIN Peptide, 1110064L01Rik Peptide, AI647969 Peptide, PDGF-C Peptide, platelet derived growth factor C Peptide, platelet-derived growth factor, C polypeptide Peptide, PDGFC Peptide, Pdgfc Peptide
- Target Type
- Viral Protein
- Background
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Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen and chemoattractant for cells of mesenchymal origin. Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate. Required for normal skin morphogenesis during embryonic development. Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling. Plays an important role in angiogenesis and blood vessel development. Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs. The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain. In the nucleus, PDGFC seems to have additional function.
Alias Symbols: 1110064L01Rik, AI647969, PDGF-C
Protein Size: 345 - Molecular Weight
- 39 kDa
- Gene ID
- 54635
- NCBI Accession
- NM_019971, NP_064355
- UniProt
- Q8CI19
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