(1 reference)-
- Target See all CLIP products
- CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
- Protein Region
- AA 86-100
- Sequence
- PVSKMRMATP LLMQA
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Storage
- -20°C
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: "Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 5097-106, (2013) (PubMed).
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: "Structure-based design of altered MHC class II-restricted peptide ligands with heterogeneous immunogenicity." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 10, pp. 5097-106, (2013) (PubMed).
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- Target
- CLIP (Corticotropin-Like Intermediate Peptide (CLIP))
- Background
- This is amino acids 86 to 100 fragment of class II-associated invariant chain peptide called CLIP. The major histocompatibility complex class II molecule displays peptide fragments of foreign proteins to trigger a defensive reaction from the immune system. Before insertion of the foreign peptides into the binding groove, a place-holding peptide CLIP is removed. This is accomplished by the molecule DM, which is shown to increase the dissociation rate of a CLIP peptide from class II.
- Molecular Weight
- 1674.100
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