Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) Peptide
GNRH1
1 image
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- Target See all GNRH1 products
- GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))
- Purity
- > 95 %
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Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1) peptide (Ovalbumin)
GNRH1 Reactivity: Human Host: Synthetic Imm, SDS, WB
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- Restrictions
- For Research Use only
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- Storage
- -20 °C
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- Target
- GNRH1 (Gonadotropin-Releasing Hormone 1 (Luteinizing-Releasing Hormone) (GNRH1))
- Synonyms
- GNRH Peptide, GRH Peptide, HH12 Peptide, LHRH Peptide, LNRH Peptide, Gnrh Peptide, Gnrh2 Peptide, Lhrh1 Peptide, Lnrh Peptide, hpg Peptide, Gnrha Peptide, Lhrh Peptide, Rgnrhg1 Peptide, CGNRH-I Peptide, GnRH-I Peptide, GnRH Peptide, gnrh Peptide, gnrh1 Peptide, grh Peptide, lhrh Peptide, lnrh Peptide, mdGnRH Peptide, mdgnrh Peptide, mfGnRH Peptide, gonadotropin releasing hormone 1 Peptide, gonadotropin releasing hormone 1 L homeolog Peptide, prepro-gonadotropin-releasing hormone Peptide, GNRH1 Peptide, Gnrh1 Peptide, gnrh1.L Peptide, gnrh1 Peptide
- Background
- LH-RH is a hypothalamic peptide that stimulates release of gonadotrophins from anterior pituitary, thus regulating reproductive functions. It has been assumed, usually with good reason, that D-amino acids with large aromatic side-chains must be present in position 6 of both LH-RH superagonists and antagonists for the highest levels of biological activity to be reached. However, using one of a recent generation of potent lH-RH inhibitory analogs as a model, we have found that the insertion of D-lysine or, better still, D-arginine in this position results in greater antiovulatory activity in the rat over corresponding D-phenylalanine6- and D-tryptophan6-analogs.
- CAS-No
- 86073-88-3
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