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Substance P (AA 1-9) Peptide

Catalog No. ABIN399825
  • Target See all Substance P products
    Substance P
    Protein Region
    AA 1-9
    Purity
    > 95 %
  • Restrictions
    For Research Use only
  • Storage
    -20 °C
  • Target
    Substance P
    Synonyms
    Hs.2563 Peptide, NK2 Peptide, NKNA Peptide, NPK Peptide, TAC2 Peptide, PPTA3 Peptide, Ppt5fl Peptide, RATPPTA3 Peptide, TAC Peptide, 4930528L02Rik Peptide, NK-1 Peptide, NK1 Peptide, Nkna Peptide, PPT-A Peptide, PPTA Peptide, SP Peptide, PPT Peptide, beta-PPT-A Peptide, NKA Peptide, tachykinin precursor 1 Peptide, tachykinin, precursor 1 Peptide, tachykinin 1 Peptide, TAC1 Peptide, Tac1 Peptide
    Background
    Subtance P is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. NK-1 agonist, potent vasodilator and hypotensive agent, induces salivation, putative neurotransmitter in sensory (pain) afferents. Substance P(1-9) is a fragment of Subtance P. Accumulating evidence shows that N- and C-terminal substance P fragments have significant biological activity. Substance P(1-9) has been reported to be major substance P metabolites in rat striatum and it has modulatory effects similar to substance P.
    CAS-No
    57468-17-4
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