Mitochondrial Ribosomal Protein L50 (MRPL50) (N-Term) Peptide
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- Target See all MRPL50 products
- MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CREFWSRFRK EKEPVVVETV EEKKEPILVC PPLRSRAYTP PEDLQSRLES
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-RM50 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))
- Synonyms
- ANON-65Eb Peptide, BcDNA:GM06185 Peptide, BcDNA:RE06140 Peptide, CG8612 Peptide, Dmel\\CG8612 Peptide, MRP-L50 Peptide, anon-65Eb Peptide, DKFZp468B0910 Peptide, AA408971 Peptide, AI317351 Peptide, D4Wsu125e Peptide, mitochondrial ribosomal protein L50 Peptide, mitochondrial 54S ribosomal protein MRPL50 Peptide, mRpL50 Peptide, Mrpl50 Peptide, MRPL50 Peptide
- Background
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Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.
Alias Symbols: MRPL50,
Protein Size: 158 - Gene ID
- 54534
- NCBI Accession
- NP_061924
- UniProt
- Q8N5N7
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