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Mitochondrial Ribosomal Protein L50 (MRPL50) (N-Term) Peptide

MRPL50 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5510976
  • Target See all MRPL50 products
    MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))
    Protein Region
    N-Term
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    CREFWSRFRK EKEPVVVETV EEKKEPILVC PPLRSRAYTP PEDLQSRLES
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-RM50 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MRPL50 (Mitochondrial Ribosomal Protein L50 (MRPL50))
    Synonyms
    ANON-65Eb Peptide, BcDNA:GM06185 Peptide, BcDNA:RE06140 Peptide, CG8612 Peptide, Dmel\\CG8612 Peptide, MRP-L50 Peptide, anon-65Eb Peptide, DKFZp468B0910 Peptide, AA408971 Peptide, AI317351 Peptide, D4Wsu125e Peptide, mitochondrial ribosomal protein L50 Peptide, mitochondrial 54S ribosomal protein MRPL50 Peptide, mRpL50 Peptide, Mrpl50 Peptide, MRPL50 Peptide
    Background
    Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75 % protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

    Alias Symbols: MRPL50,

    Protein Size: 158
    Gene ID
    54534
    NCBI Accession
    NP_061924
    UniProt
    Q8N5N7
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