CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD) (Middle Region) Peptide
CRADD
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CRADD products
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- PAGDRLTGIP SHILNSSPSD RQINQLAQRL GPEWEPMVLS LGLSQTDIYR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CRADD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CRADD (CASP2 and RIPK1 Domain Containing Adaptor with Death Domain (CRADD))
- Synonyms
- cradd Peptide, MGC89035 Peptide, zgc:101717 Peptide, CRADD Peptide, DKFZp468A2219 Peptide, LOC100226369 Peptide, raidd Peptide, MGC78788 Peptide, MRT34 Peptide, RAIDD Peptide, CASP2 and RIPK1 domain containing adaptor with death domain Peptide, CASP2 and RIPK1 domain containing adaptor with death, gene 1 Peptide, CASP2 and RIPK1 domain containing adaptor with death, gene 2 S homeolog Peptide, CRADD Peptide, cradd.1 Peptide, cradd Peptide, cradd.2.S Peptide, Cradd Peptide
- Background
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The protein encoded by this gene is a death domain (CARD/DD)-containing protein and has been shown to induce cell apoptosis. Through its CARD domain, this protein interacts with, and thus recruits, caspase 2/ICH1 to the cell death signal transduction complex that includes tumor necrosis factor receptor 1 (TNFR1A), RIPK1/RIP kinase, and numbers of other CARD domain-containing proteins.
Alias Symbols: CRADD, RAIDD,
Protein Size: 199 - Gene ID
- 8738
- NCBI Accession
- NP_003796
- UniProt
- P78560
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