Sialophorin (SPN) (Middle Region) Peptide
SPN
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CD43 (SPN) products
- CD43 (SPN) (Sialophorin (SPN))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LVALLLLWRR RQKRRTGALV LSRGGKRNGV VDAWAGPAQV PEEGAVTVTV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SPN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CD43 (SPN) (Sialophorin (SPN))
- Synonyms
- CD43 Peptide, GALGP Peptide, GPL115 Peptide, LSN Peptide, A630014B01Rik Peptide, Cd43 Peptide, Galgp Peptide, Ly-48 Peptide, Ly48 Peptide, Lsn Peptide, Lsn1 Peptide, gpL115 Peptide, sialophorin Peptide, SPN Peptide, Spn Peptide
- Background
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One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1. During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response.
Protein Size: 400 - Gene ID
- 105369261
- NCBI Accession
- NM_001030288, NP_001025459
- UniProt
- P16150
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