Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1) (Middle Region) Peptide
MCL1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all MCL-1 (MCL1) products
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- EELDGYEPEP LGKRPAVLPL LELVGESGNN TSTDGSLPST PPPAEEEEDE
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- MCL1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))
- Synonyms
- BCL2L3 Peptide, EAT Peptide, MCL1-ES Peptide, MCL1L Peptide, MCL1S Peptide, Mcl-1 Peptide, TM Peptide, bcl2-L-3 Peptide, mcl1/EAT Peptide, AW556805 Peptide, mcl-1 Peptide, fb72f02 Peptide, wu:fb70a08 Peptide, wu:fb72f02 Peptide, zfMLP1 Peptide, zfMcl-1a Peptide, zgc:109835 Peptide, zgc:109763 Peptide, E3 Peptide, E3-2 Peptide, RNE3 Peptide, RNU107 Peptide, SNORA63A Peptide, elF-4AII Peptide, MCL1, BCL2 family apoptosis regulator Peptide, myeloid cell leukemia sequence 1 Peptide, MCL1, BCL2 family apoptosis regulator a Peptide, MCL1, BCL2 family apoptosis regulator b Peptide, small nucleolar RNA, H/ACA box 63 Peptide, MCL1 Peptide, Mcl1 Peptide, mcl1a Peptide, mcl1b Peptide, SNORA63 Peptide
- Background
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This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Alias Symbols: TM, EAT, MCL1L, MCL1S, Mcl-1, BCL2L3, MCL1-ES, bcl2-L-3, mcl1/EAT
Protein Size: 271 - Gene ID
- 4170
- NCBI Accession
- NM_001197320, NP_001184249
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