Vascular Endothelial Growth Factor A (VEGFA) (C-Term) Peptide
VEGFA
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all VEGFA products
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- ECRPKKDRAR QEKKSVRGKG KGQKRKRKKS RYKSWSVYVG ARCCLMPWSL
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-VEGFA Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- VEGFA (Vascular Endothelial Growth Factor A (VEGFA))
- Synonyms
- MVCD1 Peptide, VEGF Peptide, VPF Peptide, Vegf Peptide, Vegf120 Peptide, Vegf164 Peptide, Vegf188 Peptide, Vpf Peptide, vegf Peptide, vegfa Peptide, wu:fj82c06 Peptide, VEGF-A Peptide, VEGF164 Peptide, eVEGF120 Peptide, eVEGF164 Peptide, vegf-a Peptide, vpf Peptide, vefg Peptide, si:dkey-14d8.3 Peptide, wu:fd42e02 Peptide, vascular endothelial growth factor A Peptide, vascular endothelial growth factor Aa Peptide, vascular endothelial growth factor A L homeolog Peptide, vascular endothelial growth factor Ab Peptide, VEGFA Peptide, Vegfa Peptide, vegfaa Peptide, vegfa.L Peptide, vegfa Peptide, vegfab Peptide
- Background
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This gene is a member of the PDGF/VEGF growth factor family and encodes a protein that is often found as a disulfide linked homodimer. This protein is a glycosylated mitogen that specifically acts on endothelial cells and has various effects, including mediating increased vascular permeability, inducing angiogenesis, vasculogenesis and endothelial cell growth, promoting cell migration, and inhibiting apoptosis. Elevated levels of this protein is linked to POEMS syndrome, also known as Crow-Fukase syndrome. Mutations in this gene have been associated with proliferative and nonproliferative diabetic retinopathy. Alternatively spliced transcript variants, encoding either freely secreted or cell-associated isoforms, have been characterized. There is also evidence for the use of non-AUG (CUG) translation initiation sites upstream of, and in-frame with the first AUG, leading to additional isoforms.
Alias Symbols: Name=VEGFA,
Protein Size: 327 - Gene ID
- 7422
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