Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) Peptide
Quick Overview for Aminolevulinate, delta-, Synthase 1 (ALAS1) (N-Term) Peptide (ABIN8094538)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- ALAS1 Peptide - N-terminal region
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Sequence
- RALSTAAVHY QQIKETPPAS EKDKTAKAKV QQTPDGSQQS PDGTQLPSGH
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-ALAS1 Antibody (ARP72388_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
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Background
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Background Information: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme, a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Alternative Symbols: ALAS1, ALAS3, ALASH, OK/SW-cl.121,
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Molecular Weight
- 70kDa
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Gene ID
- 211
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NCBI Accession
- XP_005265002
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UniProt
- P13196
Target
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