Aminolevulinate, delta-, Synthase 1 (ALAS1) Peptide
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- Target See all ALAS1 products
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ALAS1 antibody (Catalog #: ARP54346_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
: "
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Renal Function Decline With Small Interfering RNA Silencing Aminolevulinic Acid Synthase 1 (ALAS1)." in: Kidney international reports, Vol. 6, Issue 7, pp. 1904-1911, (2021) (PubMed).
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- Target
- ALAS1 (Aminolevulinate, delta-, Synthase 1 (ALAS1))
- Synonyms
- ALAS Peptide, ALAS3 Peptide, ALASH Peptide, MIG4 Peptide, ALAS-N Peptide, Alas-1 Peptide, Alas-h Peptide, ALAS-H Peptide, ALASN Peptide, ALAS1 Peptide, wu:fb58d01 Peptide, wu:fi12g09 Peptide, 5'-aminolevulinate synthase 1 Peptide, aminolevulinic acid synthase 1 Peptide, alanyl-tRNA synthetase protein Peptide, aminolevulinate, delta-, synthase 1 Peptide, ALAS1 Peptide, Alas1 Peptide, alas1 Peptide, alas1.S Peptide, alaS1 Peptide
- Background
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Delta-aminolevulinate synthase (ALAS, EC 2.3.1.37) catalyzes the condensation of glycine with succinyl-CoA to form delta-aminolevulinic acid. This nuclear-encoded mitochondrial enzyme is the first and rate-limiting enzyme in the mammalian heme biosynthetic pathway. There are 2 tissue-specific isozymes: a housekeeping enzyme encoded by the ALAS1 gene and an erythroid tissue-specific enzyme encoded by ALAS2.
Alias Symbols: ALAS, ALAS3, ALASH, MIG4
Protein Interaction Partner: STAMBP
Protein Size: 640 - Molecular Weight
- 70 kDa
- Gene ID
- 211
- NCBI Accession
- NM_000688, NP_000679
- UniProt
- P13196
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