Amyloid beta (A4) Precursor-Like Protein 2 (APLP2) (Middle Region) Peptide
APLP2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all APLP2 products
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DEEEGEEVVE DRDYYYDTFK GDDYNEENPT EPGSDGTMSD KEITHDVKAV
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-APLP2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- APLP2 (Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
- Synonyms
- HAI Peptide, MT-SP1 Peptide, MTSP1 Peptide, PRSS14 Peptide, SNC19 Peptide, TADG15 Peptide, TMPRSS14 Peptide, APLP-2 Peptide, APPH Peptide, APPL2 Peptide, CDEBP Peptide, AI790698 Peptide, Apph Peptide, WALPLP2 Peptide, aplp2 B Peptide, APLP2 Peptide, si:dkey-11k4.3 Peptide, aplp2 A Peptide, MGC86389 Peptide, suppression of tumorigenicity 14 Peptide, amyloid beta precursor like protein 2 Peptide, amyloid beta (A4) precursor-like protein 2 Peptide, amyloid beta (A4) precursor-like protein 2 S homeolog Peptide, amyloid beta (A4) precursor-like protein 2 L homeolog Peptide, ST14 Peptide, APLP2 Peptide, Aplp2 Peptide, aplp2.S Peptide, aplp2 Peptide, aplp2.L Peptide
- Background
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This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: APLP2,APPL2,
Protein Size: 761 - Gene ID
- 334
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