Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) Peptide
Quick Overview for Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) Peptide (ABIN5512325)
Target
Origin
Source
Application
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Protein Region
- C-Term
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Sequence
- GLKLLSWLGS IIGYSDGLRR ILCQVGLQEG PDGENSSLVD RLMLSDSKLW
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Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBR2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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Background
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Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.
Protein Size: 439 -
Gene ID
- 23304
Target
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