Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) Peptide
UBR2
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all UBR2 products
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-UBR2 antibody (Catalog #: ARP43188_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
- Synonyms
- ba49a4.1 Peptide, si:ch211-239i4.2 Peptide, C6orf133 Peptide, RP3-392M17.3 Peptide, bA49A4.1 Peptide, dJ242G1.1 Peptide, dJ392M17.3 Peptide, 9930021A08Rik Peptide, AI462103 Peptide, AW540746 Peptide, E130209G04Rik Peptide, mKIAA0349 Peptide, ubiquitin protein ligase E3 component n-recognin 2 Peptide, ubiquitin protein ligase E3 component n-recognin 2 S homeolog Peptide, UBR2 Peptide, ubr2 Peptide, ubr2.S Peptide, Ubr2 Peptide
- Background
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Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron (Kwon et al., 2003 [PubMed 14585983]).[supplied by OMIM].
Alias Symbols: C6orf133, DKFZp686C08114, KIAA0349, MGC71112, RP3-392M17.3, bA49A4.1, dJ242G1.1, dJ392M17.3
Protein Interaction Partner: UBE2B,HNRNPA1,UBE2B
Protein Size: 1755 - Molecular Weight
- 200 kDa
- Gene ID
- 23304
- NCBI Accession
- NM_015255, NP_056070
- UniProt
- Q8IWV8
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