Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) Peptide
UBR2
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN8115168
$145.08
Plus shipping costs $50.00
100 μg
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Quick Overview for Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2) (C-Term) Peptide (ABIN8115168)
Target
UBR2
(Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- C-Term
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Purpose
- UBR2 Peptide - C-terminal region
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Sequence
- GLKLLSWLGS IIGYSDGLRR ILCQVGLQEG PDGENSSLVD RLMLSDSKLW
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-UBR2 Antibody (ARP43187_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))
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Background
- Proteolysis by the ubiquitin-proteasome system controls the concentration of many regulatory proteins. The selectivity of ubiquitylation is determined by ubiquitin E3 ligases, which recognize the substrate's destabilization signal, or degron. The E3 ligase UBR2 participates in the N-end rule pathway, which targets proteins bearing an N-terminal degron, or N-degron.
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Molecular Weight
- 48kDa
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Gene ID
- 23304
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UniProt
- Q8IWV8
Target
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