Notochord Homeobox (NOTO) (C-Term) Peptide
NOTO
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all NOTO products
- NOTO (Notochord Homeobox (NOTO))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CSGLWAFPDW APTEDLQDTE RQQKRVRTMF NLEQLEELEK VFAKQHNLVG
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-NOTO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- NOTO (Notochord Homeobox (NOTO))
- Synonyms
- Xnot-2 Peptide, Xnot2 Peptide, not Peptide, nota Peptide, noto Peptide, RGD1562910 Peptide, Xnot Peptide, Flh Peptide, MmNot Peptide, Not Peptide, tc Peptide, Znot Peptide, flh Peptide, notochord homeobox Peptide, notochord homeobox S homeolog Peptide, NOTO Peptide, not.S Peptide, Noto Peptide, not Peptide, noto Peptide
- Background
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NOTO is a transcription regulator acting downstream of both FOXA2 and T during notochord development. It is required for node morphogenesis. It is essential for cilia formation in the posterior notochord (PNC) and for left-right patterning, it acts upstream of FOXJ1 and RFX3 in this process and is required for the expression of various components important for axonemal assembly and function. And it plays a role in regulating axial versus paraxial cell fate (By similarity).
Alias Symbols: NOTO,
Protein Size: 251 - Gene ID
- 344022
- NCBI Accession
- NP_001127934
- UniProt
- A8MTQ0
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