Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1) (Middle Region) Peptide
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- Target See all PLEKHA1 products
- PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- WVNVLNKAIK ITVPKQSDSQ PNSDNLSRHG ECGKKQVSYR TDIVGGVPII
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- PLEKHA1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- PLEKHA1 (Pleckstrin Homology Domain Containing, Family A (phosphoinositide Binding Specific) Member 1 (PLEKHA1))
- Synonyms
- RGD1564153 Peptide, fc34a05 Peptide, fc57h12 Peptide, zgc:55676 Peptide, wu:fc34a05 Peptide, wu:fc57h12 Peptide, MGC83674 Peptide, PLEKHA1 Peptide, DKFZp459M1025 Peptide, TAPP1 Peptide, AA960558 Peptide, C920009D07Rik Peptide, pleckstrin homology domain containing A1 Peptide, pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1a Peptide, pleckstrin homology domain containing A1 S homeolog Peptide, pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 Peptide, Plekha1 Peptide, plekha1a Peptide, PLEKHA1 Peptide, plekha1.S Peptide, plekha1 Peptide
- Background
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This gene encodes a pleckstrin homology domain-containing adapter protein. The encoded protein is localized to the plasma membrane where it specifically binds phosphatidylinositol 3,4-bisphosphate. This protein may be involved in the formation of signaling complexes in the plasma membrane. Polymorphisms in this gene are associated with age-related macular degeneration. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 5.
Alias Symbols: TAPP1
Protein Size: 334 - Gene ID
- 59338
- NCBI Accession
- NM_001001974, NP_001001974
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