Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15) (C-Term) Peptide
TNFSF15
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all TNFSF15 products
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- CSEIRQAGRP NKPDSITVVI TKVTDSYPEP TQLLMGTKSV CEVGSNWFQP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-TNFSF15 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- TNFSF15 (Tumor Necrosis Factor (Ligand) Superfamily, Member 15 (TNFSF15))
- Synonyms
- TTPAL Peptide, TL1 Peptide, TL1A Peptide, VEGI Peptide, VEGI192A Peptide, Tl1 Peptide, Tl1a Peptide, Vegi Peptide, tumor necrosis factor superfamily member 15 Peptide, TNF superfamily member 15 Peptide, tumor necrosis factor (ligand) superfamily, member 15 Peptide, TNFSF15 Peptide, Tnfsf15 Peptide
- Background
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The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells. The expression of this protein is inducible by TNF and IL-1 alpha. This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6. It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells. This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor. Two transcript variants encoding different isoforms have been found for this gene.
Protein Size: 192 - Gene ID
- 9966
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