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Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (Middle Region) Peptide

MAP2K1 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN5672592
  • Target See all MEK1 (MAP2K1) products
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Protein Region
    Middle Region
    Origin
    Human
    Source
    • 16
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Sequence
    VEMAVGRYPI PPPDAKELEL MFGCQVEGDA AETPPRPRTP GRPLSSYGMD
    Characteristics
    This is a synthetic peptide designed for use in combination with anti- MAP2K1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
    Synonyms
    Mek1 Peptide, CFC3 Peptide, MAPKK1 Peptide, MEK1 Peptide, MKK1 Peptide, PRKMK1 Peptide, MEKK1 Peptide, Prkmk1 Peptide, mek-2 Peptide, si:ch211-242m18.2 Peptide, wu:fj56a12 Peptide, wu:fj61b01 Peptide, zgc:56557 Peptide, ATMEK1 Peptide, F20B18.180 Peptide, F20B18_180 Peptide, MAP kinase/ ERK kinase 1 Peptide, MITOGEN ACTIVATED PROTEIN KINASE KINASE Peptide, MITOGEN ACTIVATED PROTEIN KINASE KINASE 1 Peptide, NMAPKK Peptide, MEK Peptide, mitogen activated protein kinase kinase 1 Peptide, mitogen-activated protein kinase kinase 1 Peptide, mitogen-activated protein kinase kinase 1 L homeolog Peptide, MAP kinase/ ERK kinase 1 Peptide, Map2k1 Peptide, MAP2K1 Peptide, map2k1.L Peptide, map2k1 Peptide, MEK1 Peptide
    Background
    The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.

    Alias Symbols: CFC3, MEK1, MKK1, MAPKK1, PRKMK1

    Protein Size: 393
    Gene ID
    5604
    NCBI Accession
    NM_002755, NP_002746
    UniProt
    Q02750
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