Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (Middle Region) Peptide
MAP2K1
Reactivity: Human
Host: Synthetic
BP, WB
Catalog No. ABIN5672592
$160.46
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100 μg
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Quick Overview for Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1) (Middle Region) Peptide (ABIN5672592)
Target
MEK1 (MAP2K1)
(Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
Origin
Human
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB)
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Protein Region
- Middle Region
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Sequence
- VEMAVGRYPI PPPDAKELEL MFGCQVEGDA AETPPRPRTP GRPLSSYGMD
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Characteristics
- This is a synthetic peptide designed for use in combination with anti- MAP2K1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Background
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The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Alias Symbols: CFC3, MEK1, MKK1, MAPKK1, PRKMK1
Protein Size: 393 -
Gene ID
- 5604
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NCBI Accession
- NM_002755, NP_002746
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UniProt
- Q02750
Target
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