Suppressor of Fused Homolog (SUFUH) (Middle Region) Peptide
SUFUH
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all SUFUH products
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- QERVDKGIET DGSNLSGVSA KCAWDDLSRP PEDDEDSRSI CIGTQPRRLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti- SUFU Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- SUFUH (Suppressor of Fused Homolog (SUFUH))
- Synonyms
- CG6054 Peptide, Dmel\\CG6054 Peptide, SU(FU) Peptide, SUFU Peptide, Su(Fu) Peptide, SuFu Peptide, Sufu Peptide, su(fu) Peptide, sufu Peptide, Xsufu Peptide, sufuh Peptide, sufuxl Peptide, PRO1280 Peptide, SUFUH Peptide, SUFUXL Peptide, Su(fu) Peptide, dre Peptide, fi39e05 Peptide, wu:fi39e05 Peptide, 2810026F04Rik Peptide, b2b273Clo Peptide, Suppressor of fused Peptide, SUFU negative regulator of hedgehog signaling L homeolog Peptide, SUFU negative regulator of hedgehog signaling Peptide, suppressor of fused homolog (Drosophila) Peptide, Su(fu) Peptide, sufu.L Peptide, SUFU Peptide, sufu Peptide, Sufu Peptide
- Background
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The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
Alias Symbols: SUFUH, SUFUXL, PRO1280
Protein Size: 484 - Gene ID
- 51684
- NCBI Accession
- NM_001178133, NP_001171604
- UniProt
- Q9UMX1
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