BCL2-Associated Athanogene (BAG1) (N-Term) Peptide
Quick Overview for BCL2-Associated Athanogene (BAG1) (N-Term) Peptide (ABIN8095457)
Target
Origin
Source
Application
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Protein Region
- N-Term
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Purpose
- BAG1 Peptide - N-terminal region
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Sequence
- QGEEMNRSQE VTRDEESTRS EEVTREEMAA AGLTVTVTHS NEKHDLHVTS
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-BAG1 Antibody (ARP63476_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Background
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Background Information: The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X.
Alternative Symbols: HAP, RAP46
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Molecular Weight
- 38kDa
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Gene ID
- 573
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NCBI Accession
- NP_004314
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UniProt
- Q99933
Target
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