BCL2-Associated Athanogene (BAG1) Peptide
Quick Overview for BCL2-Associated Athanogene (BAG1) Peptide (ABIN8095459)
Target
Origin
Source
Application
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Purpose
- BAG1 Peptide - middlel region
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Sequence
- VPLPFQKLIF KGKSLKEMET PLSALGMQNG CRVMLIGEKS NPEEEVELKK
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti- BAG1 Antibody (ARP89672_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- BAG1 (BCL2-Associated Athanogene (BAG1))
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Background
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Background Information: The oncogene Bcl2 encodes a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to Bcl2 protein and is referred to as Bcl2-associated athanogene. It enhances the anti-apoptotic effects of Bcl2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. At least two protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) start site and an alternative, downstream, AUG translation initiation site.
Alternative Symbols: BAG-1, Rap46
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Molecular Weight
- 40 kDa
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Gene ID
- 12017
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NCBI Accession
- NP_001165210
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UniProt
- Q60739
Target
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