Premelanosome Protein (PMEL) (N-Term) Peptide
Quick Overview for Premelanosome Protein (PMEL) (N-Term) Peptide (ABIN8108878)
Target
Source
Application
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Protein Region
- N-Term
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Purpose
- SILV Peptide - N-terminal region
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Comment
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This is a synthetic peptide designed for use in combination with anti-SILV antibody ( ARP46802_T100). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications. Please inquire for more details.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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Buffer
- Lyophilized powder
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Storage
- -20 °C
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Storage Comment
- For longer periods of storage, store at -20 °C. Avoid repeat freeze-thaw cycles.
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- Melanoma gp100 (PMEL) (Premelanosome Protein (PMEL))
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Background
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Background Information: SILV could be a melanogenic enzyme. It could represent an oncofetal self-antigen that is normally expressed at low levels in quiescent adult melanocytes but overexpressed by proliferating neonatal melanocytes and during tumor growth. Release of the soluble form, ME20-S, it could protect tumor cells from antibody mediated immunity.
Alternative Symbols: D12S53E, ME20, PMEL17, SI, SIL, gp100, P1, P100, SILV, ME20M, ME20-M
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Molecular Weight
- 70kDa
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Gene ID
- 6490
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NCBI Accession
- NP_008859
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UniProt
- P40967
Target
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