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Fas (TNFRSF6)-Associated Via Death Domain (FADD) Peptide

FADD Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN936923
  • Target See all FADD products
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 6
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    ASVAGLVKAL RTCRLNLVAD LVEEAQESVS KSENMSPVLR DSTVSSSETP
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of Fadd antibody,
    Alternative Names: FADD control peptide, FADD antibody Blocking Peptide, Anti-FADD Blocking Peptide, Fas Blocking Peptide, Tnfrsf6-Associated Via Death Domain Blocking Peptide, Mort1/FADD Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    FADD (Fas (TNFRSF6)-Associated Via Death Domain (FADD))
    Synonyms
    MORT1 Peptide, Mort1/FADD Peptide, Mort1 Peptide, TNFRSF6 Peptide, adaptor Peptide, fadd Peptide, mort1 Peptide, xfadd Peptide, Fas associated via death domain Peptide, Fas (TNFRSF6)-associated via death domain Peptide, Fas associated via death domain S homeolog Peptide, Fas (tnfrsf6)-associated via death domain Peptide, FADD Peptide, Fadd Peptide, fadd.S Peptide, fadd Peptide
    Background
    Fadd is apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis.
    Molecular Weight
    23 kDa
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