Thymidylate Synthetase (TYMS) Peptide
TYMS
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
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- Target See all TYMS products
- TYMS (Thymidylate Synthetase (TYMS))
- Peptide Type
- Synthetic
- Origin
- Mammalian
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Sequence
- HIEPLKIQLQ REPRPFPKLR ILRKVEKIDD FKAEDFQIEG YNPHPTIKME
- Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of TYMS antibody,
Alternative Names: TYMS control peptide, TYMS antibody Blocking Peptide, Anti-TYMS Blocking Peptide, Thymidylate Synthetase Blocking Peptide, HsT422 Blocking Peptide, MGC88736 Blocking Peptide, TMS Blocking Peptide, TS Blocking Peptide, TSase Blocking Peptide
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- Application Notes
- Optimal conditions should be determined by the investigator
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
- Buffer
- PBS
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- -20 °C
- Storage Comment
- Store at -20 °C long term.
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- Target
- TYMS (Thymidylate Synthetase (TYMS))
- Synonyms
- FN1 Peptide, ECK2823 Peptide, JW2795 Peptide, ts Peptide, Ts Peptide, HST422 Peptide, TMS Peptide, TS Peptide, thymidylate synthetase Peptide, contains intron in T4 phage Peptide, ThyE Peptide, thymidylate synthase Peptide, thymidylate synthetase L homeolog Peptide, TYMS Peptide, thyA Peptide, td Peptide, thyE Peptide, DDA3937_RS04960 Peptide, tyms.L Peptide, XBJ1_RS15770 Peptide, EAMY_RS20680 Peptide, Tyms Peptide
- Target Type
- Viral Protein
- Background
- TYMS catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs.
- Molecular Weight
- 36 kDa
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