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Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D) Peptide

SEMA6D Reactivity: Mammalian Host: Synthetic BP, WB, IHC
Catalog No. ABIN939936
  • Target See all SEMA6D products
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    Peptide Type
    Synthetic
    Origin
    Mammalian
    Source
    • 3
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Sequence
    KLYSATVADF LASDAVIYRS MGDGSALRTI KYDSKWIKEP HFLHAIEYGN
    Characteristics
    A synthetic peptide for use as a blocking control in assays to test for specificity of SEMA6 D antibody,
    Alternative Names: SEMA6D control peptide, SEMA6D antibody Blocking Peptide, Anti-SEMA6D Blocking Peptide, Sema Domain Immunoglobulin Domain 6D Blocking Peptide, FLJ11598 Blocking Peptide, KIAA1479 Blocking Peptide, SEMA6D, SEMAD-6, SEMAD 6, SEMAD-6 Blocking Peptide, SEMAD 6 Blocking Peptide
  • Application Notes
    Optimal conditions should be determined by the investigator
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
    Buffer
    PBS
    Handling Advice
    Avoid repeated freeze/thaw cycles.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C long term.
  • Target
    SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))
    Synonyms
    1110067B02Rik Peptide, AA409156 Peptide, D330011G23 Peptide, Sema6D-1 Peptide, Sema6D-2 Peptide, Sema6D-4 Peptide, Sema6D-5 Peptide, Sema6D-6 Peptide, mKIAA1479 Peptide, wu:fi06a12 Peptide, wu:fi76a10 Peptide, zgc:56170 Peptide, semaphorin 6D Peptide, sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D Peptide, semaphorin 6D L homeolog Peptide, SEMA6D Peptide, Sema6d Peptide, sema6d Peptide, sema6d.L Peptide
    Background
    Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.
    Molecular Weight
    65 kDa
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