Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Peptide
CYP3A4
Reactivity: Mammalian
Host: Synthetic
BP, WB, IHC
Catalog No. ABIN940055
Quick Overview for Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Peptide (ABIN940055)
Target
CYP3A4
(Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
Origin
Mammalian
Source
Synthetic
Application
Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
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Peptide Type
- Synthetic
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Sequence
- KSVKRMKESR LEDTQKHRVD FLQLMIDSQN SKETESHKAL SDLELVAQSI
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Characteristics
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A synthetic peptide for use as a blocking control in assays to test for specificity of CYP3 A4 antibody,
Alternative Names: CYP3A4 control peptide, CYP3A4 antibody Blocking Peptide, Anti-CYP3A4 Blocking Peptide, Cytochrome P450 Family 3 Subfamily A Polypeptide 4 Blocking Peptide, CP33 Blocking Peptide, CP34 Blocking Peptide, CYP3A Blocking Peptide, CYP3A3 Blocking Peptide, HLP Blocking Peptide, MGC126680 Blocking Peptide, NF-25 Blocking Peptide, P450C3 Blocking Peptide, P450PCN1 Blocking Peptide, CYP3A4, CYPA4-3, CYPA4 3, CYPA4-3 Blocking Peptide, CYPA4 3 Blocking Peptide
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Application Notes
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Handling Advice
- Avoid repeated freeze/thaw cycles.
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Storage
- -20 °C
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Storage Comment
- Store at -20 °C long term.
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- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
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Background
- This gene, CYP3A4, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs which are are used today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens.
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Molecular Weight
- 57 kDa
Target
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