Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Peptide
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- Target See all CYP3A4 products
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CYP3A43 antibody (Catalog #: ARP49757_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
- Synonyms
- CP33 Peptide, CP34 Peptide, CYP3A Peptide, CYP3A3 Peptide, CYPIIIA3 Peptide, CYPIIIA4 Peptide, HLP Peptide, NF-25 Peptide, P450C3 Peptide, P450PCN1 Peptide, MGC108372 Peptide, CYP3A80 Peptide, CYP3A4 Peptide, CYP3A21 Peptide, CYPIIIA21 Peptide, CYP3A12 Peptide, cytochrome P450 family 3 subfamily A member 4 Peptide, cytochrome P450 family 3 subfamily A member 43 Peptide, cytochrome P450 3A4 Peptide, cytochrome P450, subfamily IIIA, polypeptide 4 Peptide, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 Peptide, cytochrome P450, family 3, subfamily A, polypeptide 4 Peptide, CYP3A4 Peptide, CYP3A43 Peptide, PTRG_01782 Peptide, PTRG_06060 Peptide, cyp3a4 Peptide
- Background
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CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.
Alias Symbols: MGC119315, MGC119316
Protein Size: 504 - Molecular Weight
- 58 kDa
- Gene ID
- 64816
- NCBI Accession
- NM_022820, NP_073731
- UniProt
- Q9HB55
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