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Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4) Peptide

CYP3A4 Reactivity: Human Host: Synthetic BP, WB, IHC
Catalog No. ABIN975547
  • Target See all CYP3A4 products
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Origin
    Human
    Source
    • 11
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB), Immunohistochemistry (IHC)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CYP3A43 antibody (Catalog #: ARP49758_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CYP3A4 (Cytochrome P450, Family 3, Subfamily A, Polypeptide 4 (CYP3A4))
    Synonyms
    CP33 Peptide, CP34 Peptide, CYP3A Peptide, CYP3A3 Peptide, CYPIIIA3 Peptide, CYPIIIA4 Peptide, HLP Peptide, NF-25 Peptide, P450C3 Peptide, P450PCN1 Peptide, MGC108372 Peptide, CYP3A80 Peptide, CYP3A4 Peptide, CYP3A21 Peptide, CYPIIIA21 Peptide, CYP3A12 Peptide, cytochrome P450 family 3 subfamily A member 4 Peptide, cytochrome P450 family 3 subfamily A member 43 Peptide, cytochrome P450 3A4 Peptide, cytochrome P450, subfamily IIIA, polypeptide 4 Peptide, cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4 Peptide, cytochrome P450, family 3, subfamily A, polypeptide 4 Peptide, CYP3A4 Peptide, CYP3A43 Peptide, PTRG_01782 Peptide, PTRG_06060 Peptide, cyp3a4 Peptide
    Background
    CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This enzyme has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, it is unknown whether the enzyme is also involved in xenobiotic metabolism. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing of this gene results in three transcript variants encoding different isoforms.

    Alias Symbols: MGC119315, MGC119316

    Protein Size: 504
    Molecular Weight
    58 kDa
    Gene ID
    64816
    NCBI Accession
    NM_022820, NP_073731
    UniProt
    Q9HB55
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