Ataxin 2-Binding Protein 1 (A2BP1) (Middle Region) Peptide
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- Target See all A2BP1 products
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-A2BP1 antibody (Catalog #: ARP58203_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- A2BP1 (Ataxin 2-Binding Protein 1 (A2BP1))
- Synonyms
- A2BP1 Peptide, fox1 Peptide, a2bp1 Peptide, zgc:103635 Peptide, 2BP1 Peptide, FOX-1 Peptide, FOX1 Peptide, HRNBP1 Peptide, A2bp Peptide, A2bp1 Peptide, Hrnbp1 Peptide, fox-1 Peptide, RNA binding protein, fox-1 homolog 1 Peptide, RNA binding fox-1 homolog 1 Peptide, multicopper ferroxidase Peptide, RNA binding protein, fox-1 homolog (C. elegans) 1 Peptide, RBFOX1 Peptide, rbfox1 Peptide, FOX1 Peptide, Rbfox1 Peptide
- Background
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Ataxin-2 binding protein 1(A2BP1) has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.Ataxin-2 binding protein 1 has an RNP motif that is highly conserved among RNA-binding proteins. This protein binds to the C-terminus of ataxin-2 and may contribute to the restricted pathology of spinocerebellar ataxia type 2 (SCA2). Ataxin-2 is the gene product of the SCA2 gene which causes familial neurodegenerative diseases. Ataxin-2 binding protein 1 and ataxin-2 are both localized in the trans-Golgi network. Four alternatively spliced transcript variants have been found for this gene. Additional transcript variants have been found but their full length nature has not been determined.
Alias Symbols: FOX1, HRNBP1, 2BP1, A2BP1, FOX-1
Protein Interaction Partner: ATN1,ATXN1,ATXN2,BAT2,CELF3,DMRTB1,DVL2,GCA,HNRNPF,HSFX1,KIFAP3,LZTS2,MAGED1,NOC2L,NUMBL,PCBP4,PSMF1,QKI,RBM24,RBM9,RHOXF2,TNIP1
Protein Size: 395 - Molecular Weight
- 42 kDa
- Gene ID
- 54715
- NCBI Accession
- NM_145893, NP_665900
- UniProt
- Q9NWB1
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