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Aminolevulinate, delta-, Synthase 2 (ALAS2) Peptide

ALAS2 Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973093
  • Target See all ALAS2 products
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Origin
    Human
    Source
    • 7
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-ALAS2 antibody (Catalog #: ARP41658_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    ALAS2 (Aminolevulinate, delta-, Synthase 2 (ALAS2))
    Synonyms
    anh1 Peptide, asb Peptide, xlsa Peptide, ALAS-E Peptide, ALASE Peptide, ANH1 Peptide, ASB Peptide, XLDPP Peptide, XLEPP Peptide, XLSA Peptide, alas-e Peptide, cb1063 Peptide, sau Peptide, sauternes Peptide, ALAS Peptide, Alas-2 Peptide, 5'-aminolevulinate synthase 2 Peptide, aminolevulinate, delta-, synthase 2 Peptide, aminolevulinic acid synthase 2, erythroid Peptide, alas2 Peptide, ALAS2 Peptide, Alas2 Peptide, alas2.L Peptide
    Background
    ALAS2 specifies an erythroid-specific mitochondrially located enzyme. The protein catalyzes the first step in the heme biosynthetic pathway. Defects in its gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.The product of this gene specifies an erythroid-specific mitochondrially located enzyme. The encoded protein catalyzes the first step in the heme biosynthetic pathway. Defects in this gene cause X-linked pyridoxine-responsive sideroblastic anemia. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Alias Symbols: ANH1, ASB, XLSA, ALASE, XLDPP, XLEPP, ALAS-E

    Protein Interaction Partner: RABGGTB,SUCLA2,SUCLA2

    Protein Size: 550
    Molecular Weight
    60 kDa
    Gene ID
    212
    NCBI Accession
    NM_001037967, NP_001033056
    UniProt
    P22557
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