Aquarius Homolog (AQR) (C-Term) Peptide
AQR
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all AQR products
- AQR (Aquarius Homolog (AQR))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- DTTPSETGAT STPEAIPALS ETTPTVVGAV SAPAEANTPQ DATSAPEETK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-AQR Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- AQR (Aquarius Homolog (AQR))
- Synonyms
- AW495846 Peptide, mKIAA0560 Peptide, IBP160 Peptide, fSAP164 Peptide, aquarius Peptide, aquarius intron-binding spliceosomal factor Peptide, Aqr Peptide, AQR Peptide
- Background
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AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Alias Symbols: DKFZp686B23123, IBP160, KIAA0560, fSAP164
Protein Size: 1485 - Molecular Weight
- 171 kDa
- Gene ID
- 9716
- NCBI Accession
- NM_014691, NP_055506
- UniProt
- O60306
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