Argininosuccinate Lyase (ASL) Peptide
ASL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ASL products
- ASL (Argininosuccinate Lyase (ASL))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ASL antibody (Catalog #: ARP41666_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ASL (Argininosuccinate Lyase (ASL))
- Synonyms
- ASAL Peptide, 2510006M18Rik Peptide, zgc:63532 Peptide, BA4879 Peptide, PSPTO0125 Peptide, Adl Peptide, Asl Peptide, argininosuccinate lyase Peptide, argininosuccinate lyase ArgH Peptide, adenylosuccinate lyase Peptide, argininosuccinate lyase L homeolog Peptide, ASL Peptide, Asl Peptide, asl Peptide, argH2 Peptide, argH Peptide, arg7 Peptide, CNC04420 Peptide, STHERM_c13370 Peptide, Adsl Peptide, asl.L Peptide, ARG7 Peptide
- Background
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ASL is a member of the lyase 1 family. The protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in its gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency.This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: ASAL
Protein Interaction Partner: ASL,QARS,ASL,QARS
Protein Size: 464 - Molecular Weight
- 52 kDa
- Gene ID
- 435
- NCBI Accession
- NM_000048, NP_000039
- UniProt
- P04424
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