ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1) Peptide
ATP6V0A1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all ATP6V0A1 products
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-ATP6V0A1 antibody (Catalog #: ARP46581_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- ATP6V0A1 (ATPase, H+ Transporting, Lysosomal V0 Subunit A1 (ATP6V0A1))
- Synonyms
- ATP6N1 Peptide, ATP6N1A Peptide, Stv1 Peptide, VPP1 Peptide, Vph1 Peptide, a1 Peptide, AA959968 Peptide, ATP6a1 Peptide, Atp6n1 Peptide, Atp6n1a Peptide, Atpv0a1 Peptide, Vpp-1 Peptide, Vpp1 Peptide, A1 Peptide, wu:fj37e01 Peptide, zgc:112214 Peptide, atp6v0a1 Peptide, wu:fc25b09 Peptide, zgc:76965 Peptide, ATPase H+ transporting V0 subunit a1 Peptide, ATPase, H+ transporting, lysosomal V0 subunit A1 Peptide, si:ch73-173p19.2 Peptide, ATPase, H+ transporting, lysosomal V0 subunit a1 L homeolog Peptide, ATPase, H+ transporting, lysosomal V0 subunit a1b Peptide, ATPase, H+ transporting, lysosomal V0 subunit a1a Peptide, ATP6V0A1 Peptide, Atp6v0a1 Peptide, si:ch73-173p19.2 Peptide, atp6v0a1.L Peptide, atp6v0a1b Peptide, atp6v0a1a Peptide
- Background
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ATP6V0A1 is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. ATP6V0A1 is one of three A subunit proteins and it is associated with clathrin-coated vesicles.This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three A subunit proteins and the encoded protein is associated with clathrin-coated vesicles. The occurrence of splice variants encoding different protein products has been reported, but the full-length natures of these transcripts have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ATP6N1, ATP6N1A, DKFZp781J1951, Stv1, VPP1, Vph1, a1
Protein Size: 831 - Molecular Weight
- 96 kDa
- Gene ID
- 535
- NCBI Accession
- NM_005177, NP_005168
- UniProt
- Q93050
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