UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2) (Middle Region) Peptide
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- Target See all B4GALT2 products
- B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- NRISLTGMKI SRPDIRIGRY RMIKHDRDKH NEPNPQRFTK IQNTKLTMKR
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-B4GALT2 Antibody(ARP44507_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- B4GALT2 (UDP-Gal:betaGlcNAc beta 1,4- Galactosyltransferase, Polypeptide 2 (B4GALT2))
- Synonyms
- B4Gal-T2 Peptide, B4Gal-T3 Peptide, beta4Gal-T2 Peptide, Ggtb2 Peptide, b4gal-t1 Peptide, b4galt2 Peptide, beta4gal-t1 Peptide, cdg2d Peptide, ggtb2 Peptide, gt1 Peptide, gtb Peptide, b4gal-t2 Peptide, beta4gal-t2 Peptide, b4Gal-T2 Peptide, si:ch211-261p7.4 Peptide, CKII Peptide, beta-1,4-galactosyltransferase 2 Peptide, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 Peptide, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1, gene 2 Peptide, UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 S homeolog Peptide, B4GALT2 Peptide, B4galt2 Peptide, b4galt1.2 Peptide, b4galt2.S Peptide, b4galt2 Peptide
- Background
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This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose, all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Two transcript variants encoding the same protein have been found for this gene.
Alias Symbols: B4Gal-T2, B4Gal-T3, beta4Gal-T2
Protein Size: 372 - Molecular Weight
- 42 kDa
- Gene ID
- 8704
- NCBI Accession
- NM_001005417, NP_001005417
- UniProt
- O60909
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