BCL2-Antagonist/killer 1 (BAK1) (N-Term) Peptide
BAK1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all BAK1 products
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-BAK1 antibody (Catalog #: AVARP02022_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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BCL2-Antagonist/killer 1 (BAK1) peptide
BAK1 Reactivity: Human, Mouse, Pig, Rat Host: Synthetic BP, Imm
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- BAK1 (BCL2-Antagonist/killer 1 (BAK1))
- Synonyms
- BAK Peptide, BAK-LIKE Peptide, BCL2L7 Peptide, CDN1 Peptide, Bak Peptide, N-BAK1 Peptide, N-Bak Peptide, Bak1 Peptide, bak Peptide, bak1 Peptide, BCL2 antagonist/killer 1 Peptide, BCL2-antagonist/killer 1 Peptide, BCL2 antagonist/killer 1 L homeolog Peptide, BAK1 Peptide, Bak1 Peptide, bak1.L Peptide
- Background
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BAK1 belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress.The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form oligomers or heterodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein localizes to mitochondria, and functions to induce apoptosis. It interacts with and accelerates the opening of the mitochondrial voltage-dependent anion channel, which leads to a loss in membrane potential and the release of cytochrome c. This protein also interacts with the tumor suppressor P53 after exposure to cell stress. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: BAK, BAK-LIKE, BCL2L7, CDN1, MGC117255, MGC3887
Protein Interaction Partner: BAK1,TP53,TP53,BAK1,BAX,BCL2,BCL2A1,BCL2L1,BCL2L10,BID,ERN1,HSPD1,MCL1,MFN1,TP53,VDAC1,VDAC2,ACTR2,AKAP13,BAK1,BAX,BCL2,BCL2L1,BCL2L2,DFFA,FBL,FRYL,HSPD1,KRT31,MCL1,MYCBP2,SRRM2,TP53,VDAC2
Protein Size: 211 - Molecular Weight
- 23 kDa
- Gene ID
- 578
- NCBI Accession
- NM_001188, NP_001179
- UniProt
- Q16611
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