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DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B) Peptide

DDX39B Reactivity: Human Host: Synthetic BP, WB
Catalog No. ABIN973733
  • Target See all DDX39B products
    DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
    Origin
    Human
    Source
    • 1
    Synthetic
    Application
    Blocking Peptide (BP), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-BAT1 antibody (Catalog #: ARP36372_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    DDX39B (DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 39B (DDX39B))
    Synonyms
    BAT1 Peptide, D6S81E Peptide, UAP56 Peptide, Bat1 Peptide, Bat1a Peptide, p47 Peptide, 0610030D10Rik Peptide, AI428441 Peptide, Bat-1 Peptide, D17H6S81E Peptide, D17H6S81E-1 Peptide, D6S81Eh Peptide, bat1 Peptide, zgc:63773 Peptide, DExD-box helicase 39B Peptide, DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B Peptide, DDX39B Peptide, Ddx39b Peptide, ddx39b Peptide
    Background
    BAT1 is a member of the DEAD protein family of ATP-dependent RNA helicases. Members of this family are involved in a number of cellular functions including initiation of translation, RNA splicing, and ribosome assembly. A cluster of genes, BAT1-BAT5, has been localized in the vicinity of the genes for TNF alpha and TNF beta. These genes are all within the human major histocompatibility complex class III region. This protein is a negative regulator of inflammation. It is also thought to be a translation initiation factor. This gene is a strong candidate gene for rheumatoid arthritis. There are multiple alternatively spliced transcript variants known for this gene but only two have been fully described. Both of these variants encode the same isoform. This gene has been found to have multiple polyadenylation sites.

    Alias Symbols: BAT1, UAP56, D6S81E

    Protein Interaction Partner: THOC4,U2AF2,BAT1,DDX39,DNM2,EXOSC9,HIPK2,HNRPLL,PIAS2,RBM39,RPS15A,SARNP,SFRS12,STRN4,TDG,THOC4,TUBB3,YWHAG,ZHX1,DNM2,FANCA,STRN4,THOC4,TUBB3

    Protein Size: 428
    Molecular Weight
    47 kDa
    Gene ID
    7919
    NCBI Accession
    NM_080598, NP_542165
    UniProt
    Q13838
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