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Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18) Peptide

CCL18 Reactivity: Human Host: Synthetic BP, IHC, WB
Catalog No. ABIN974583
  • Target See all CCL18 products
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Origin
    Human
    Source
    Synthetic
    Application
    Blocking Peptide (BP), Immunohistochemistry (IHC), Western Blotting (WB)
    Characteristics
    This is a synthetic peptide designed for use in combination with anti-CCL18 antibody (Catalog #: AVARP07049_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    Purification
    Purified
  • Application Notes
    Each Investigator should determine their own optimal working dilution for specific applications.
    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    Concentration
    1 mg/mL
    Buffer
    Final peptide concentration is 1 mg/mL in PBS.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • Target
    CCL18 (Chemokine (C-C Motif) Ligand 18 (Pulmonary and Activation-Regulated) (CCL18))
    Synonyms
    H7AP1 Peptide, PARC Peptide, RP3-330M21.2 Peptide, AMAC-1 Peptide, AMAC1 Peptide, CKb7 Peptide, DC-CK1 Peptide, DCCK1 Peptide, MIP-4 Peptide, SCYA18 Peptide, cullin 9 Peptide, C-C motif chemokine ligand 18 Peptide, CUL9 Peptide, CCL18 Peptide
    Background
    CCL18 is one of several Cys-Cys (CC) cytokine genes clustered on the q arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by CCL18 displays chemotactic activity for naive T cells, CD4+ and CD8+ T cells and nonactivated lymphocytes, but not for monocytes or granulocytes. This chemokine attracts naive T lymphocytes toward dendritic cells and activated macrophages in lymph nodes. It may play a role in both humoral and cell-mediated immunity responses.

    Alias Symbols: CKb7, PARC, AMAC1, DCCK1, MIP-4, AMAC-1, DC-CK1, SCYA18

    Protein Interaction Partner: C14orf1,CRMP1,EEF1A1,TLE1,TP53,UNC119,C14orf1,CRMP1,EEF1A1,TLE1,TP53,UNC119

    Protein Size: 89
    Molecular Weight
    10 kDa
    Gene ID
    6362
    NCBI Accession
    NM_002988, NP_002979
    UniProt
    P55774
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