Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1) (Middle Region) Peptide
-
- Target See all E-cadherin (CDH1) products
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- Protein Region
- Middle Region
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- FSHAVSSNGN AVEDPMEILI TVTDQNDNKP EFTQEVFKGS VMEGALPGTS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CDH1 Antibody(ARP59265_P050),. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- E-cadherin (CDH1) (Cadherin 1, Type 1, E-Cadherin (Epithelial) (CDH1))
- Synonyms
- Arc-1 Peptide, CD324 Peptide, CDHE Peptide, ECAD Peptide, LCAM Peptide, UVO Peptide, E-cadherin Peptide, cdh1 Peptide, si:dz180o5.2 Peptide, uvo Peptide, lcam Peptide, E-Cad Peptide, XBcad Peptide, l-cam Peptide, xcdh1 Peptide, cdhc-A Peptide, xb-cad Peptide, XTCAD-1 Peptide, c-cadherin Peptide, cadherin-1 Peptide, uvomorulin Peptide, XB-cadherin Peptide, arc-1 Peptide, cd324 Peptide, cdhe Peptide, ecad Peptide, AA960649 Peptide, E-cad Peptide, Ecad Peptide, L-CAM Peptide, Um Peptide, cadherin 1 Peptide, si:busm1-180o5.2 Peptide, cadherin 1, type 1, E-cadherin (epithelial) Peptide, cadherin 1, type 1 S homeolog Peptide, CDH1 Peptide, si:busm1-180o5.2 Peptide, cdh1 Peptide, Cdh1 Peptide, cdh1.S Peptide
- Background
-
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7.
Alias Symbols: Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Protein Interaction Partner: ZEB1,CAV1,CTNNB1,CTNNB1,CTNNB1,CTNND1,EGFR,ACTR3,ANAPC7,ARHGAP32,ARVCF,CA9,CASP3,CASP8,CBLL1,CDH1,CSE1L,CSNK2A1,CTNNA1,CTNNB1,CTNND1,CTNND2,EGFR,ERBB2IP,EZR,GNA12,GNA13,GSK3B,HDAC1,HDAC2,IQGAP1,IRS1,ITGAE,ITGB7,JUP,NDRG1,NEDD9,PKD1,PPP1CA,PSEN1,PTPN14,PTP
Protein Size: 882 - Molecular Weight
- 80 kDa
- Gene ID
- 999
- NCBI Accession
- NM_004360, NP_004351
- UniProt
- P12830
-