Ceramide Kinase-Like (CERKL) (N-Term) Peptide
CERKL
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CERKL products
- CERKL (Ceramide Kinase-Like (CERKL))
- Protein Region
- N-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- TLDLINLSED HCDIWFRQFK KILAGFPNRP KSLKILLNPQ SHKKEATQVY
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CERKL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CERKL (Ceramide Kinase-Like (CERKL))
- Synonyms
- RGD1561057 Peptide, Gm1958 Peptide, Rp26 Peptide, GB19002 Peptide, RP26 Peptide, zgc:162213 Peptide, ceramide kinase like Peptide, ceramide kinase-like Peptide, ceramide kinase Peptide, CERKL Peptide, Cerkl Peptide, LOC408315 Peptide, CERK Peptide, LOC100566923 Peptide, LOC100645684 Peptide, cerkl Peptide
- Background
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This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.
Alias Symbols: RP26
Protein Size: 532 - Molecular Weight
- 59 kDa
- Gene ID
- 375298
- NCBI Accession
- NM_201548, NP_963842
- UniProt
- Q49MI3
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