Collagen, Type IV, alpha 3 (COL4A3) (Middle Region) Peptide
COL4A3
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all COL4a3 (COL4A3) products
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Protein Region
- Middle Region
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- YRADDANVVR DRDLEVDTTL KSLSQQIENI RSPEGSRKNP ARTCRDLKMC
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COL4A3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COL4a3 (COL4A3) (Collagen, Type IV, alpha 3 (COL4A3))
- Synonyms
- zTumstatin Peptide, [a]3(IV) Peptide, alpha3(IV) Peptide, collagen type IV alpha 3 chain Peptide, collagen, type IV, alpha 3 Peptide, COL4A3 Peptide, col4a3 Peptide, Col4a3 Peptide
- Background
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This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.
Alias Symbols: -
Protein Interaction Partner: CAPN1,BGN,BMP1,CAPN1,CD36,CD44,CD93,COL7A1,DCN,DDR2,FGF7,FN1,HTRA1,IGFBP3,ITGA2,ITGA5,MATN2,MMP2,MMP9,NID1,P4HB,PAK1,PDGFB,PRELP,SPARC,TGFBI,THBS1,TMPRSS6,TXN,VWF,COL7A1,IGFBP3,ITGA2,ITGB1,MAG,MATN2,MMP2,NID1,NID2,Nid1,PKD1,PRELP,SPARC,THBS1,TXN,VWF
Protein Size: 1464 - Molecular Weight
- 137 kDa
- Gene ID
- 1285
- NCBI Accession
- NM_031362, NP_112730
- UniProt
- E7ENN2
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