Collagen, Type IX, alpha 1 (COL9A1) (N-Term) Peptide
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- Target See all COL9A1 products
- COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))
- Protein Region
- N-Term
- Origin
- Human
- Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- GADGLTGPDG SPGSIGSKGQ KGEPGVPGSR GFPGRGIPGP PGPPGTAGLP
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-COL9A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- COL9A1 (Collagen, Type IX, alpha 1 (COL9A1))
- Synonyms
- cb339 Peptide, sb:cb339 Peptide, zgc:85892 Peptide, wu:fa12a12 Peptide, wu:fa12d02 Peptide, wu:fc22c08 Peptide, wu:fc38d08 Peptide, edm6 Peptide, MGC82441 Peptide, DJ149L1.1.2 Peptide, EDM6 Peptide, MED Peptide, STL4 Peptide, Col9a-1 Peptide, collagen, type IX, alpha 1b Peptide, collagen, type IX, alpha 1 L homeolog Peptide, collagen type IX alpha 1 chain Peptide, collagen, type IX, alpha 1 Peptide, collagen alpha-1(IX) chain Peptide, col9a1b Peptide, col9a1.L Peptide, COL9A1 Peptide, Col9a1 Peptide, LOC101102992 Peptide
- Background
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This gene encodes one of the three alpha chains of type IX collagen, which is a minor (5-20 % ) collagen component of hyaline cartilage. Type IX collagen is usually found in tissues containing type II collagen, a fibrillar collagen. Studies in knockout mice have shown that synthesis of the alpha 1 chain is essential for assembly of type IX collagen molecules, a heterotrimeric molecule, and that lack of type IX collagen is associated with early onset osteoarthritis. Mutations in this gene are associated with osteoarthritis in humans, with multiple epiphyseal dysplasia, 6, a form of chondrodysplasia, and with Stickler syndrome, a disease characterized by ophthalmic, orofacial, articular, and auditory defects. Two transcript variants that encode different isoforms have been identified for this gene.
Alias Symbols: DJ149L1.1.2, EDM6, FLJ40263, MED, STL4
Protein Size: 678 - Molecular Weight
- 62 kDa
- Gene ID
- 1297
- NCBI Accession
- NM_078485, NP_511040
- UniProt
- A6NEQ6
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