Chemokine (C-X-C Motif) Ligand 12 (CXCL12) Peptide
CXCL12
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CXCL12 products
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CXCL12 antibody (Catalog #: AVARP07031_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CXCL12 (Chemokine (C-X-C Motif) Ligand 12 (CXCL12))
- Synonyms
- IRH Peptide, PBSF Peptide, SCYB12 Peptide, SDF1 Peptide, TLSF Peptide, TPAR1 Peptide, CINC-1 Peptide, Gro1 Peptide, Pbsf Peptide, Scyb12 Peptide, Sdf1 Peptide, Tlsf Peptide, Tpar1 Peptide, Fsp Peptide, KC Peptide, Mgsa Peptide, N51 Peptide, Scyb1 Peptide, gro Peptide, sdf-1 Peptide, sdf1 Peptide, xSDF-1 Peptide, SDF-1 Peptide, cxcl12 Peptide, sdf-1a Peptide, sdf1a Peptide, wu:fa55e10 Peptide, wu:fc16h12 Peptide, wu:fj84c02 Peptide, C-X-C motif chemokine ligand 12 Peptide, C-X-C motif chemokine ligand 1 Peptide, chemokine (C-X-C motif) ligand 12 Peptide, chemokine (C-X-C motif) ligand 1 Peptide, C-X-C motif chemokine ligand 12 L homeolog Peptide, chemokine (C-X-C motif) ligand 12a (stromal cell-derived factor 1) Peptide, CXCL12 Peptide, cxcl12 Peptide, Cxcl1 Peptide, Cxcl12 Peptide, cxcl12.L Peptide, cxcl12a Peptide
- Background
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Stromal cell-derived factors 1-alpha and 1-beta are small cytokines that belong to the intercrine family, members of which activate leukocytes and are often induced by proinflammatory stimuli such as lipopolysaccharide, TNF, or IL1. The intercrines are characterized by the presence of 4 conserved cysteines which form 2 disulfide bonds. They can be classified into 2 subfamilies. In the CC subfamily, which includes beta chemokine, the cysteine residues are adjacent to each other. In the CXC subfamily, which includes alpha chemokine, they are separated by an intervening amino acid. The SDF1 proteins belong to the latter group.
Alias Symbols: IRH, PBSF, SDF1, TLSF, SDF1A, SDF1B, TPAR1, SCYB12
Protein Interaction Partner: CXCR4,CD4,CTSG,CXCL12,CXCR4,DPP4,ELANE,FN1,MMP2,CXCL12,FN1,PF4,VCAN
Protein Size: 93 - Molecular Weight
- 11 kDa
- Gene ID
- 6387
- NCBI Accession
- NM_000609, NP_000600
- UniProt
- P48061
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