Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) (C-Term) Peptide
CYP24A1
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all CYP24A1 products
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- LNTKVWQDHT LAWDTIFKSV KACIDNRLEK YSQQPSADFL CDIYHQNRLS
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-CYP24A1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- Synonyms
- CP24 Peptide, CYP24 Peptide, HCAI Peptide, P450-CC24 Peptide, 24-OHase Peptide, Cyp24 Peptide, 25-hydroxyvitaminD324-hydroxylase Peptide, VITD12 Peptide, CP450CC24 Peptide, cytochrome P450 family 24 subfamily A member 1 Peptide, cytochrome P450, family 24, subfamily a, polypeptide 1 Peptide, cytochrome P450, family 24, subfamily A, polypeptide 1 Peptide, CYP24A1 Peptide, Cyp24a1 Peptide
- Background
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CYP24A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system.
Alias Symbols: CP24, CYP24, MGC126273, MGC126274, P450-CC24, HCAI
Protein Size: 514 - Molecular Weight
- 55 kDa
- Gene ID
- 1591
- NCBI Accession
- NM_000782, NP_000773
- UniProt
- Q07973
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