Diazepam Binding Inhibitor (DBI) (N-Term) Peptide
-
- Target See all Diazepam Binding Inhibitor (DBI) products
- Diazepam Binding Inhibitor (DBI)
- Protein Region
- N-Term
- Origin
- Human
-
Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Sequence
- MWGDLWLLPP ASANPGTGTE AEFEKAAEEV RHLKTKPSDE EMLFIYGHYK
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DBI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
-
-
- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
- Target
- Diazepam Binding Inhibitor (DBI)
- Synonyms
- ACBD1 Peptide, ACBP Peptide, CCK-RP Peptide, EP Peptide, dbib Peptide, DBI Peptide, wu:fb63e10 Peptide, zgc:56108 Peptide, zgc:77734 Peptide, Acbp Peptide, endozepine Peptide, Acoabp3 Peptide, Ep Peptide, Odn Peptide, RNACOABP3 Peptide, Ttn Peptide, acbd1 Peptide, acbp Peptide, cck-rp Peptide, dbi Peptide, dbi-a Peptide, dbi-b Peptide, dbia Peptide, diazepam binding inhibitor, acyl-CoA binding protein Peptide, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog Peptide, diazepam-binding inhibitor Peptide, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) Peptide, acyl-CoA-binding protein Peptide, diazepam binding inhibitor Peptide, diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog Peptide, DBI Peptide, dbi.S Peptide, dbi Peptide, LOC706367 Peptide, Dbi Peptide, dbi.L Peptide
- Background
-
DBI is diazepam binding inhibitor. The protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. DBI is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ACBD1, ACBP, CCK-RP, EP, MGC70414
Protein Interaction Partner: PPCDC,TSPO
Protein Size: 104 - Molecular Weight
- 12 kDa
- Gene ID
- 1622
- NCBI Accession
- NM_020548, NP_065438
- UniProt
- B8ZWD2
-