DNA Cross-Link Repair 1C (DCLRE1C) (C-Term) Peptide
DCLRE1C
Reactivity: Human
Host: Synthetic
BP, WB
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- Target See all DCLRE1C products
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
- Protein Region
- C-Term
- Origin
- Human
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Source
- Synthetic
- Application
- Blocking Peptide (BP), Western Blotting (WB)
- Characteristics
- This is a synthetic peptide designed for use in combination with anti-DCLRE1C antibody (Catalog #: ARP51165_P050). It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
- Purification
- Purified
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- Application Notes
- Each Investigator should determine their own optimal working dilution for specific applications.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- Concentration
- 1 mg/mL
- Buffer
- Final peptide concentration is 1 mg/mL in PBS.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Target
- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
- Synonyms
- artemis Peptide, A-SCID Peptide, DCLREC1C Peptide, RS-SCID Peptide, SCIDA Peptide, SNM1C Peptide, hSNM1C Peptide, Snm1l Peptide, nuclease Peptide, 9930121L06Rik Peptide, AI661365 Peptide, Art Peptide, DNA cross-link repair 1C Peptide, DCLRE1C Peptide, Dclre1c Peptide
- Background
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DCLRE1C is a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA). This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The protein has single-strand-specific 5'-3' exonuclease activity, it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins when complexed with protein kinase, DNA-activated, catalytic polypeptide. Mutations in this gene cause Athabascan-type severe combined immunodeficiency (SCIDA).
Alias Symbols: A-SCID, DCLREC1C, FLJ11360, FLJ36438, RS-SCID, SCIDA, SNM1C, hSNM1C
Protein Interaction Partner: TP53BP1,ATM,BRCA1,MRE11A,NBN,PRKDC,RAD50,TP53BP1,PRKDC
Protein Size: 572 - Molecular Weight
- 65 kDa
- Gene ID
- 64421
- NCBI Accession
- NM_001033857, NP_001029029
- UniProt
- Q96SD1
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